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pentobarbital will lessen the extent or effect of saxagliptin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.pentobarbital will decrease the extent or influence of ethotoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.pentobarbital will lower the extent or impact of naloxegol by